Octreotide for bowel obstruction

A randomised, double-blind, placebo-controlled trial of infusional subcutaneous octreotide in the management of malignant bowel obstruction in people with advanced cancer.

DOI	10.58084/fv1e-ac81
Type of DOI	dataset
Publisher	Palliative Care Clinical Studies Collaborative (PaCCSC)
Creators	Professor David Currow
Date made available	2024
Description of dataset	Data set includes individual participant data for 112 consenting participants CSV files for the number of days free of vomiting as reported by patients daily, measured 72 hours after the first administration of study medication patient-rated Global Impression of Change the number of patient-reported episodes of vomiting survival as date of death nausea and Pain scores using NCI CTCAE criteria and Brief Pain Inventory functional status (Australian modified Karnofsky Performance Scale (AKPS) protocol defined “as needed” symptom control medications (hyoscine butylbromide for colicky pain, morphine for pain, haloperidol for nausea) quality of life measures used the EORTC C15, Facit Pal caregiver quality of life was measured using the Caregiver Quality of Life Index data is available for screening, baseline, each day of intervention, and four weeks of follow up health service utilisation data was collected for up to 4 weeks post intervention.
Funding	Australian Government
Subject (ANZCTR category)	Gastroenterology and hepatology
ANZCTR reference	ACTRN12621001403820
Main trial page	PaCCSC clinical trials
Publications	Clinician-reported changes in octreotide prescribing for malignant bowel obstruction as a result of an adequately powered phase III study: A transnational, online survey Double-blind, placebo-controlled, randomized trial of octreotide in malignant bowel obstruction Octreotide for Malignant Bowel Obstruction: Commentary on Currow et al
Dataset access	Access can be requested via the Health Data Australia catalogue. Search for the ACTRN number in the catalogue to find datasets associated with these trials or email enquiries to hesanda@uts.edu.au.

Acknowledgement of Country

UTS acknowledges the Gadigal people of the Eora Nation, the Boorooberongal people of the Dharug Nation, the Bidiagal people and the Gamaygal people, upon whose ancestral lands our university stands. We would also like to pay respect to the Elders both past and present, acknowledging them as the traditional custodians of knowledge for these lands.