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Transcriptome Research
miRNA Targets and RNA-based Cancer Diagnostics
Transcriptome research is a fast-growing field of scientific enquiry. Research in this field is building an international reputation for its ability to identify and characterise non-coding RNAs. These nucleic acids are key regulators of gene expression in virtually all biological processes, including development, diseases and immunity.
Bio-Informatics
The Bio-informatics team is focused on extracting value from large-scale connected biomedical data through the use of efficient data mining algorithms. Research areas include conformational B-cell epitope prediction, protein binding hotspot prediction, gene expression data analysis and ICU decision-making systems. This work makes a significant contribution to structural biology, gene regulation understanding, diagnostic and prognostic biomarker identification, and disease gene prioritisation.
Notable projects in this stream include investigations into cell-to-cell communications, delivery of therapeutics via small RNAs, and the use of non-coding RNAs as biomarkers for prostate and head and neck cancer.